The 2nd annual Phenome 2018 conference will bring together a multidisciplinary community comprising plant biologists, ecologists, engineers, agronomists, computer scientists, and representatives from U.S. federal agencies in a rich and diverse networking environment to foster collaboration, innovation, and the initiation of multi-investigator and multi-institution projects. Phenome 2018 will also serve as a platform to generate greater understanding about plants and climate change. The conference will bring together preeminent speakers from Asia, Europe, and North America.